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AperionDx

Protein Detection Redefined

Proven. Compatible. Scalable Diagnostics.

1.5-4 hrs
Turnaround Time
up to 350
Samples per plate
≥ 97.5%
PPA / NPA
None
New hardware

*Validated against Simoa® and ELISA with PPA/NPA ≥ 97.5% for Traumatic Brain Injury and Alzheimer's Disease under specified conditions.

Protein-PCR Aβ40 Aβ42 pTau181 pTau217 GFAP ALDOC NGRN BDNF ST2 1.5-4 Hour TAT up to 350 Samples / Plate Protein-PCR Aβ40 Aβ42 pTau181 pTau217 GFAP ALDOC NGRN BDNF ST2 1.5-4 Hour TAT up to 350 Samples / Plate

What We Do

Protein Detection at Scale

AperionDx develops innovative diagnostic solutions that make protein detection more sensitive, more reliable*, faster and effortlessly scalable.

Powered by Protein-PCR™, our solutions work on the qPCR instruments you already own, transforming existing infrastructure into a global protein-measurement network with minimal setup, no new hardware, and easy rollout across single labs or multi-site programs.

*Validated against Simoa® and ELISA with PPA/NPA ≥ 97.5% for Traumatic Brain Injury and Alzheimer's Disease under specified conditions.

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Illustration of a DNA double helix

Key Differentiators

Why Protein-PCR?

01

Ultimate Sensitivity

Redefines the state-of-the-art sensitivity (LOD) for important TBI and AD protein biomarkers.

02

Accessible

Runs on widely available, generic qPCR systems; no expensive, proprietary hardware required .

03

Comprehensive

Detects multiple key biomarkers in a single well via a cost-effective workflow.

04

Clinically Aligned

Designed to complement imaging and Cerebrospinal Fluid (CSF) assays for diagnostic accuracy and research insight.

05

Scalable

High-throughput testing for research and clinical settings with 1.5-4 hour Turnaround Time.

Our Partners

Trusted by innovators in biotech and life science research

We collaborate with leading institutions to accelerate breakthroughs in diagnostics

  • U.S. Air Force
  • AFWERX
  • MTEC — Medical Technology Enterprise Consortium
  • XPRIZE Foundation
  • PBL Assay Science
  • Biomedica CRO

How it Works

The Science Behind Protein-PCR

Protein-PCR enables ultra-sensitive detection of disease biomarkers using standard qPCR instruments already present in laboratories worldwide. This innovation enables rapid, accessible, sensitive and scalable biomarker testing, delivering results in a few hours. Each assay is designed to maximize both operational simplicity as well as exquisite analytical sensitivity and specificity for its intended target analytes.

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A scientist pipetting samples at a laboratory bench

Use Cases

Where Innovation Meets Impact

Why We're Here

We're building high-sensitivity, precision diagnostics that are affordable, scalable, and clinically rigorous, so labs can detect and monitor disease faster.

Research labs can probe with greater sensitivity. We pair Protein-PCR with the qPCR systems you already have to help your team move faster from question to answer, making high-quality testing more accessible and eventually improving patient care.

Laboratory bench with sample vials and a monitor displaying molecular analysis

Contact Us

Ready to Redefine Diagnostics?